Information for Healthcare Professionals


Skelaxin Safety & Side Effects

Safety and Side Effects of SKELAXIN® 800mg (metaxalone) Tablets

SKELAXIN® is non-narcotic and nonaddicting.6,12 There are other benefits, such as:
  • No risk of dependence6,12
  • No withdrawal symptoms6,12
  • No adverse cardiovascular effects6
  • No dry mouth, urinary retention, or blurred vision6
  • No interactions with monoamine oxidase inhibitors6
As with all prescription medicines, there are also adverse effects.
  • Taking SKELAXIN® with food may enhance general CNS depression. Elderly patients may be especially susceptible to this effect6
  • The most frequent reactions are nausea, vomiting, gastrointestinal upset, drowsiness, dizziness, headache, and nervousness or "irritability"6